Pyrrole Reaction Exploration and Development
Files
Document Type
Abstract
Publication Date
10-2-2019
Abstract
The project “Exploration and Development of Pyrroles” was a subproject within Dr. Jeff Hansen’s research project “Diversity Oriented Synthesis of Biologically Active Compounds”. This specific project was comprised of conducting various organic synthesis reactions using ketone epoxide and several different aniline species all for the purpose of making pyrrole products. The goal for this project was to further investigate the making of several types of pyrrole products as well as learn more about how these reactions occur and how cleanly the reaction could produce pyrrole products depending on the type of aniline used. I also tested to learn if the products were biological activity which could indicate if a compound is pharmaceutically useful. In order to achieve this goal, I reacted several aniline species with ketone epoxide and analyzed the products. In addition, I used a Brine Shrimp Lethality Assay to test the biological activity of the certain pyrrole products. #30-42 OFF CAMPUS EXPERIENCES AND PRACTICUMS =Additional Poster authors but non-DPU related
Project Mentor
Prof. J. Hansen, PhD
Recommended Citation
Leonard, Mary, "Pyrrole Reaction Exploration and Development" (2019). Annual Student Research Poster Session. 185.
https://scholarship.depauw.edu/srfposters/185
Funding and Acknowledgements
Funding: Howard and Lucile Burkett Endowed Research Fund