Urinary Sodium Excretion: Finding an Inclusive Equation in Older Populations

Urinary Sodium Excretion: Finding an Inclusive Equation in Older Populations

Document Type

Abstract

Publication Date

10-2-2019

Abstract

Current methods of urinary sodium analysis utilize a 24-hour urine collection, exhaustive of time and resources for clinicians and patients. In order to make assessment more efficient, methods using timed voids are being examined and show promising results. Although more efficient, many studies lack inclusivity in approach and analysis that generalizes populations independent of influencing identities and risk factors associated with intersectionality. In this study we aim to examine urinary sodium excretion subjective to age, race, gender and hypertension. Individuals ages 45- 79 from the Chicago area, participating in 2 cohort cardiovascular studies provided timed void spot samples. These samples were then analyzed for urinary sodium excreted and compared by various timed void combinations, race and sex. The model equation of a sister study built in a younger population was applied as well. Findings from all comparisons illustrated the variance occurring by over generalizations in analysis as well as the need for age diversified studies. Women’s predicted values best follow the observed values, specifically in white women. Men’s variation from the observed were worse, particularly in white men. This study emphasizes including intersectionality respective to populations for a more comprehensive understanding of urinary equation modeling and sodium consumption. Applying equations from other populations fails to incorporate risk factors that influence populations and therefore cannot be successfully employed in populations of differing demographics. Finding a generalizable equation is a necessity if we wish to monitor and improve sodium consumption on a population level.

Project Mentor

Norrina B. Allen, PhD and Amy E. Krefman

Funding and Acknowledgements

Funding: CDC and Northwestern Feinberg School of Medicine

Urinary Sodium Excretion: Finding an Inclusive Equation in Older Populations

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