Comparative Synthesis of MIL-100 Fe from Iron (III) and Ground Iron Characterization and Porous Property Evaluation

Authors

Animesh Dali '24, DePauw UniversityFollow
Khanh Nguyen '24, DePauw University
Hilary J. Eppley, DePauw UniversityFollow

Files

Document Type

Poster

Publication Date

12-4-2023

Abstract

MIL-100(Fe) is an iron-based metal-organic framework (MOF) known for its porous structure, crucial in various applications like gas storage, catalysis, drug delivery, and pollutant adsorption. In medical contexts, MIL-100(Fe) can encapsulate drugs, safeguarding them from unwanted interactions. These frameworks release drugs in specific conditions, ensuring targeted delivery. Our study investigated drug encapsulation using isoniazid (INH) and a structurally similar drug, Acetaminophen. We employed XRD, SEM imaging, Fourier Transform Infrared Spectroscopy, and UV-Vis Spectroscopy for material characterization and to probe drug absorption and delivery mechanisms.

Funding and Acknowledgements

We extend our sincere gratitude to Professor Hilary Eppley, Professor Ken Brown from the DePauw University Department of Geoscience, Maren Pink from the Indiana University Molecular Structure Center, and the Department of Chemistry and Biochemistry for their invaluable support and contribution to this project.

Recommended Citation

Dali, Animesh '24; Nguyen, Khanh '24; and Eppley, Hilary J., "Comparative Synthesis of MIL-100 Fe from Iron (III) and Ground Iron Characterization and Porous Property Evaluation" (2023). Annual Student Research Poster Session. 199.
https://scholarship.depauw.edu/srfposters/199